The following pictures are the settings we used to calibrate the Vizio D Series 4k UHD LED TV. They will work well for all kinds of content. If you want to use these settings for gaming, use the 'Game' picture mode instead of 'Calibrated.'
The 'Calibrated' picture mode is the closest to the look we want to achieve (color temperature of 6500k). You should adjust the 'Backlight' setting to your liking; higher values will be better for bright rooms and for overcoming reflections on the screen. We used '0' for sharpness, since we could spot some signs of over-sharpening with any other values. For cable TV and DVDs, though, '25' gave us better, less blurry picture.
Setting 'Color Temperature' to 'Normal' gave us the warm look we were after. The other values will bring a colder/bluer picture. We preferred to leave 'Active LED Zones' (local dimming) off, since it tended to darken some small highlights, but feel free to turn it on if you want deeper blacks. Use the 'Reduce Judder' option to add the soap opera effect and smooth out 24Hz-30Hz content (Blu-ray and DVD movies). For cable TV and DVDs, 'Reduce Noise' will help to reduce compression artifacts. Turn on 'Game Low Latency' to get the least input lag (more responsiveness) when playing video games (also, for even lower input lag, use the HDMI 5 input for video games). 'Film Mode' didn't help remove judder in our tests, but there is a chance this could be fixed in the future. You can leave it 'On,' although it is 'Off' in our screenshot.
The following are the results of the white balance and colorspace calibration on our unit. They are provided for reference, and should not be copied as the calibration values vary per individual unit even for the same model and same size as the TV we reviewed due to manufacturing tolerances. If you want to try them you will need to enter all values shown, as all of them are active at the same time. If you end up with worse picture quality, simply reset them to the default values.