The Keychron M5 is a wireless vertical mouse designed for productivity and gaming. Its vertical shape is designed to keep your hand in a 'handshake' position, which can help reduce wrist and arm tension after longer periods of use. It uses the flagship PixArt PAW3950 sensor and a Realtek 8762G MCU and supports a maximum polling rate of 8000Hz. It also has a secondary scroll wheel for horizontal scrolling.
Our Verdict
The Keychron M5 is very good for work. Its vertical shape keeps your wrist and arm in a 'handshake' position, which can help prevent strain after long periods of use. It has great build quality overall, and it connects wirelessly with the included 2.4GHz USB receiver or using Bluetooth with up to four devices simultaneously. It has a secondary wheel on the left side of the mouse, which is handy for horizontal scrolling. Its main scroll wheel, unfortunately, lacks a couple of useful extra features, like a free-scrolling mode and L/R tilt inputs.
Comfortable vertical shape.
Connects wirelessly with its USB receiver or via Bluetooth.
Great build quality.
Secondary scroll wheel for horizontal scrolling.
Main scroll wheel lacks L/R tilt inputs and free scrolling.
The Keychron M5 is a great mouse for FPS gaming. It has outstanding raw performance overall, with remarkably low click latency and an accurate and extremely responsive sensor that supports up to an 8000Hz polling rate. That said, it's rather heavy, and while its vertical design can help reduce strain over long sessions, it's not the easiest to maneuver and make the quick and precise adjustments necessary for competitive twitch shooters.
Great build quality.
Fantastic raw performance.
Heavy.
While not primarily designed for it, the Keychron M5 is a good mouse for MMO gaming. It has great build quality and a comfortable vertical shape that can help prevent strain over long sessions. It delivers superb raw performance, but it doesn't have nearly as many side buttons as bespoke MMO gaming mice.
Comfortable vertical shape.
Great build quality.
Fantastic raw performance.
Fewer side buttons than dedicated MMO mice.
The Keychron M5 has outstanding raw performance. It supports a maximum polling rate of 8000Hz and has superb click and sensor latency, making it well-suited for casual or competitive titles in any genre.
Incredible click latency.
Remarkable sensor latency and precision.
Changelog
- Updated Mar 10, 2026: We've converted this review to Test Bench 1.5.2. This update removes the Delay To Start Of Movement and Delay To End Of Movement measurements from the Sensor Latency test. See our full 1.5.2 changelog for details.
- Updated Aug 19, 2025: We've converted this review to Test Bench 1.5.1. This update removes less relevant or redundant elements, including several videos. We've also adjusted our Sensor Latency testing, resulting in minor score changes. See our full 1.5.1 changelog for details.
- Updated Jun 02, 2025: Review published.
- Updated May 28, 2025: Early access published.
Check Price
Differences Between Sizes And Variants
The Keychron M5 is available in Black or White color options. We bought and tested the White model. See a photo of our unit's label.
Popular Mouse Comparisons
The Keychron M5 is a fairly unusual product in that it's a vertical mouse designed to reduce strain after long work days, but also boasts the top-of-the-line specs and performance of a flagship gaming mouse. The other mouse on the market that has the same selling points is the Razer Pro Click Vertical V2, but the two mice take different approaches to their vertical design, and the Razer is positioned further upmarket with more premium materials and a higher price tag. Other vertical options include the Logitech Lift and the Logitech MX Vertical, but those mice don't have nearly the same gaming chops as the Keychron.
For more recommendations, check out our picks for the best ergonomic mice, the best wireless gaming mice, and the best work mice.
The Razer Pro Click V2 Vertical and the Keychron M5 are wireless vertical mice designed for gaming and productivity. Shape-wise, the Razer is more vertical at a ~72° angle, while the Keychron is at a ~47° angle. The Razer is also bigger and heavier, and it uses more premium materials with better build quality, although both mice are comfortable for a range of hand sizes. The Keychron is slightly better for gaming overall, thanks to its better click latency, sensor latency, 8000Hz polling rate, and smoother gliding mouse feet.
The Keychron M5 and the Keychron M6 are wireless mice designed for productivity and gaming. The M6 has a more traditional right-handed design, while the M5 has a vertical shape that you hold in a neutral 'handshake' position that can reduce strain over long periods. The M6 has slightly better work functionality thanks to its scroll wheel that can toggle between a free-scrolling mode and a regular notched mode, compared to the M5's traditional scroll wheel. On the other hand, the M5 has better gaming performance, with an 8000Hz polling rate and much lower click and sensor latency.
The Logitech MX Vertical and the Keychron M5 are wireless vertical mice. The Keychron is designed for both gaming and productivity, while the Logitech is designed for productivity more distinctly. As a result, the Keychron has significantly better raw performance that's on par with top-of-the-line gaming mice, while Logitech is just suitable for casual gaming. Shape-wise, the Logitech is significantly bigger and bulkier feeling, making it only suitable for larger hand sizes, while the Keychron is much more accommodating.
The Logitech Lift and the Keychron M5 are wireless vertical mice. While the Logitech is designed primarily for productivity, the Keychron is designed for both productivity and gaming. As such, it delivers outstanding raw performance that's suitable for gaming in any genre or competitive level, while the Logitech is only suitable for casual gaming. The Logitech has a smaller overall shape, but both mice are well-suited for a fairly wide range of hand sizes. The Keychron has a second scroll wheel on its left side for horizontal scrolling.
Test Results
for pictures & test results
for pictures & test results
for pictures & test results
for videos & test results
