The Vaxee ZYGEN NP-01S Wireless (4K) is a lightweight wireless gaming mouse. It shares the same right-handed, asymmetrical shape as the original Vaxee ZYGEN NP-01S, with a flattened top, somewhat narrow middle, and a small supportive hump toward the back right end. This new model brings an updated sensor package and support for a higher maximum polling rate of 4000Hz. Like other mice in Vaxee's catalog, this mouse is driverless, meaning you don't need to install software to change settings. Instead, you can adjust several sensor settings with buttons on the mouse's underside.
Our Verdict
The Vaxee NP-01S Wireless (4k) is adequate for work but isn't designed for it. That said, it has excellent build quality and wireless connectivity via a USB receiver. However, you need to connect the wireless receiver with an included cable, which takes up considerable space and can be awkward for some setups. Additionally, it lacks Bluetooth connectivity, doesn't support multi-device pairing, and its scroll wheel is missing productivity features like free-scrolling and left/right tilt inputs.
- Excellent build quality.
- No Bluetooth connectivity.
- Scroll wheel lacks free-scrolling and left/right tilt inputs.
The Vaxee NP-01S Wireless (4k) is an outstanding FPS gaming mouse. It has remarkably good sensor latency and click latency performance, providing a consistent and highly responsive feeling experience for casual or competitive play. It's also driverless, so you don't need to install configuration software. Instead, you can adjust a series of sensor settings with button combinations directly on the mouse itself. Although it's slightly heavier than some other FPS mice, the weight is well-distributed and shouldn't hinder quick, accurate movements—unless you strongly prefer mice under 65g.
- Excellent build quality.
- Outstanding click latency.
- Outstanding sensor latency.
- No software to install; can adjust sensor settings directly on the mouse.
- Limited to four CPI presets.
- Slightly heavier than similar high-end FPS mice.
The Vaxee NP-01S Wireless (4k) isn't designed specifically for MMO gaming and has far fewer side buttons than a dedicated MMO mouse. That said, it has excellent build quality, outstanding raw performance, and a comfortable, supportive shape well-suited for medium and smaller-sized hands.
- Excellent build quality.
- Outstanding click latency.
- Outstanding sensor latency.
- No software to install; can adjust sensor settings directly on the mouse.
- Fewer side buttons than a dedicated MMO gaming mouse.
- Limited to four CPI presets.
The Vaxee NP-01S Wireless (4k) offers superb raw performance. It has remarkably good and consistent all-around sensor latency, supports a maximum polling rate of 4000Hz, and provides remarkably low click latency that's more than suitable for competitive play.
- Outstanding click latency.
- Outstanding sensor latency.
Changelog
- Updated Aug 19, 2025: We've converted this review to Test Bench 1.5.1. This update removes less relevant or redundant elements, including several videos. We've also adjusted our Sensor Latency testing, resulting in minor score changes. See our full 1.5.1 changelog for details.
- Updated Oct 15, 2024: We fixed an error in which we incorrectly listed the CPI adjustment steps as 400 CPI when there are actually only four preset CPI settings.
- Updated Aug 15, 2024: Review published.
- Updated Jul 29, 2024: Early access published.
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Differences Between Sizes And Variants
The Vaxee ZYGEN NP-01S Wireless (4K) is available in Black, White, Pink, Yellow, Blue, and Orange color options. We bought and tested the Orange color, and you can see the label for our unit here.
Note that this mouse is also available in a larger version, the ZYGEN NP-01 (4k). We expect our performance tests to be broadly applicable to this version as well.
Popular Mouse Comparisons
The Vaxee ZYGEN NP-01S Wireless (4K) is a lightweight wireless gaming mouse that continues Vaxee's NP-01S lineup. Like other Vaxee releases, this mouse is driverless and doesn't have configuration software. Instead, you can change a focused series of adjustments using button combinations directly on the mouse. This is beneficial for competitive players who typically aren't allowed to use the software during tournament play or anyone else who doesn't want to install the often bloated and resource-intensive software options from other major gaming mouse manufacturers.
Its asymmetrical shape features a very flat top and significantly less aggressive rearward hump compared to more aggressive 'ergo' shapes, like the similarly sized BenQ ZOWIE EC3, the Xlite V3 Mini, or the Pwnage StormBreaker. This mouse is a high-end, high-performance option aimed squarely at competitive gamers. It's a bit heavier than competing models but is a standout option if you prefer a smaller, non-symmetrical shape and simple onboard settings control.
For more recommendations, see our picks for the best mouse, best gaming mouse, and best wireless gaming mouse.
The Logitech G PRO X SUPERLIGHT 2 and the Vaxee ZYGEN NP-01S Wireless (4K) are high-end wireless gaming mice with comparable raw performance. The Logitech is lighter and has a symmetrical shape but relies on configuration software for sensor adjustment. It also uses optical switches, which are noticeably heavier-feeling, and some may feel are comparatively mushy tactile experience. Comparatively, the Vaxee has an asymmetrical shape and provides slightly better raw performance but is driverless, allowing you to make sensor adjustments directly on the mouse with button combinations.
The BenQ ZOWIE EC2-DW and the Vaxee ZYGEN NP-01S Wireless (4K) are wireless gaming mice with right-handed shapes. The Vaxee's shape has a considerably lower profile than the ZOWIE, and its hump is flatter and further towards the rear. This gives it a smaller feel in-hand and allows for more flexibility for hybrid grip types. That said, the ZOWIE is significantly lighter than the Vaxee. The two have similar superb performance, but the Vaxee has marginally better click latency.
The Razer DeathAdder V3 Pro and the Vaxee ZYGEN NP-01S Wireless (4K) are high-end, wireless gaming mice. The Razer is larger but also a bit lighter. It has a more aggressive shape with a larger rearward hump and uses configuration software for sensor adjustments. Additionally, its maximum polling rate is only 1000Hz out of the box unless you purchase an additional HyperPolling Dongle, which increases the maximum wireless polling rate to 8000Hz. On the other hand, the Vaxee supports a maximum wireless polling rate of 4000Hz out of the box. It's also driverless, which means it lacks software and you make senor adjustments using button combinations directly on the mouse itself.
The Vaxee ZYGEN NP-01S Wireless (4K) and the Vaxee XE-S Wireless (4K) are lightweight wireless gaming mice. The XE-S has a symmetrical shape while the NP-01S has a right-handed shape with a supportive hump towards the bottom right side. The two perform similarly, but the XE-S has a newer sensor and marginally lower sensor latency.
Test Results
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